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Several MR studies using genome-wide association study (GWAS) data of European ancestry have established a causal effect of MDD on T2DM, confirmed by robust sensitivity analyses excluding horizontal pleiotropy, with 36.5% of the effect mediated by BMI [58,59,60]

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Further analysis using Western blotting indicates that BPC-157 may activate the FAK (focal adhesion kinase) and paxillin proteins